Ace The SPEX Exam

Be prepared for the Federation of State Medical Boards® with 5,735 Questions that our experts have selected to simulate the real exam.

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About the Question Bank

Our review is designed to help you maximize your score on the SPEX Exam. StatPearls questions and articles are based on our experts review of the Federation of State Medical Boards® topics. Each review course is designed to empower you to assess your knowledge and understanding of medical principles and concepts found on the SPEX Exam.

Multiple-choice questions

We have 5,735 Multiple-choice 1st, 2nd, and 3rd order questions with four detailed teaching points linked to 3,253 PubMed indexed review articles related to the SPEX Examination. You can customize practice questions to system and clinical SPEX Student subject areas. In addition, you will have access to a pre- and post-test SPEX Exam to help you target learning and identify areas that need further study. Analytics and reports allow you to compare your scores to other students.

Achieve top scores

The StatPearls SPEX prep questions, SPEX review questions, and SPEX test questions will help you achieve a top score on the SPEX Examination. 2,388 authors and 64 editors have contributed to the development of the SPEX Exam content, which is continuously refined and updated to improve your learning experience.

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SPEX Exam Overview

  • How many hours is the SPEX Exam?

    The SPEX Exam is 6 hours.

  • How many questions is the SPEX Exam?

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SPEX Exam MCQs (5,735)

Our question bank for the SPEX Exam covers four Cognitive Difficulty Levels:

Level 1

27 Questions

Level 2

551 Questions

Level 3

4,139 Questions

Level 4

1,018 Questions

  • Allergy and Immunology - 284 questions
  • Cardiovascular - 1507 questions
  • Musculoskeletal - 1019 questions
  • Ears Nose and Throat - 297 questions
  • Endocrine and Metabolism - 723 questions
  • Ophthalmology - 250 questions
  • Gastrointestinal and Nutrition - 1241 questions
  • Renal, Urinary and Electrolytes - 644 questions
  • Human Growth and Development - 215 questions
  • Gynecologic - 243 questions
  • Hematology and Oncology - 965 questions
  • Infectious Diseases - 1529 questions
  • Skin & Subcutaneous Tissue - 570 questions
  • Nervous - 1324 questions
  • Pregnancy, Childbirth & Puerperium - 221 questions
  • Psychiatric/Behavioral & Substance Use Disorder - 512 questions
  • Pulmonary & Critical Care - 913 questions
  • Poisoning & Environmental Exposure - 819 questions
  • Biostatistics and Epidemiology - 193 questions
  • Dental - 30 questions
  • Reproductive - 82 questions
  • Sexuality and Gender - 20 questions
  • Social Sciences (Ethics/Legal/Professional) - 90 questions
  • Traumatic Injuries - 222 questions
  • Manage Care and Comply Regulations - 133 questions
  • Promote Safety and Minimize Infection - 133 questions
  • Health Promotion & Maintenance (Prevent Problems) - 349 questions
  • Basic Care and Comfort (Assist Daily Living Tasks) - 44 questions
  • Pharm/Parenteral Therapy (Drugs/Vital Signs) - 1098 questions
  • Reduction Risk (Post Procedure) - 96 questions
  • Physiological Adaptation (Care Ill Patients) - 4187 questions
  • Psychosocial (Mental Health Patient/Family) - 299 questions
  • Professional Practice - 117 questions
  • Process (Analysis, Assess, Eval, Implement, Plan) - 5206 questions
  • Caring (Hope and Support) - 41 questions
  • Communication/Documentation (Oral, Written, EMR) - 53 questions
  • Teaching/Learning (Promotes Behavior Change) - 52 questions
  • Culture/Spiritualilty (Beliefs, Practices, Ethics) - 17 questions
  • Causes - 3461 questions
  • Classification - 519 questions
  • Differential - 3413 questions
  • Evaluation Diagnostic Tests - 1776 questions
  • Evaluation Lab - 1942 questions
  • Evaluation Monitoring - 580 questions
  • Evaluation Nuclear Medicine - 19 questions
  • Evaluation Procedures - 1091 questions
  • Evaluation Radiologic - 1660 questions
  • Health Maint Prevention Public Health - 257 questions
  • History Physical - 6677 questions
  • Legal - 51 questions
  • Patient Education - 392 questions
  • Prognosis Complications - 3361 questions
  • Toxicology - 348 questions
  • Treatment Medical - 3307 questions
  • Treatment Occupation/Physical Therapy - 61 questions
  • Treatment Prehospital/EMS/Disaster - 59 questions
  • Treatment Radiation - 27 questions
  • Treatment Rehabilitation - 36 questions
  • Treatment Surgical - 727 questions
  • Healthcare Ethics - 62 questions
  • Clinical Education - 132 questions
  • Environmental - 28 questions
  • Palliative - 37 questions
  • Treatment Manipulative - 11 questions
  • Airway Management - 62 questions
  • Pain Management - 80 questions
  • Sedation and Analgesic Management - 21 questions
  • Organ and Tissue Donation - 4 questions
  • Ventilatory Management - 29 questions
  • Research and Evidence-Based Medicine - 68 questions
  • Resource Utilization - 26 questions
  • Vulnerable Populations - 83 questions
  • Therapeutics (Drug treatment) - 1763 questions
  • Biostatics and Calculations - 16 questions
  • Drug Information - 1158 questions
  • Pharmaceutics (Safely dosing medications) - 438 questions
  • Pharmacokinetics (Drug movement in body) - 239 questions

SPEX Exam Articles (3,253)

We link each review question to its peer-reviewed, PubMed-indexed article from StatPearls authors and editors.
We make it easy for you to reinforce topic areas you excel at and fill knowledge gaps with source material.